How is poor oral hygiene linked to pancreatic cancer risk?

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Pancreatic cancer begins in the pancreatic tissue and is known to be aggressive in nature. Early detection of pancreatic cancer is challenging, and it usually remains undetected until the later stages. Symptoms of pancreatic cancer in the later stages include yellowing of the skin, pain in the upper abdomen, dark urine, itchy skin, nausea, and fatigue. It is important to identify the contributing factors to fight the risk of pancreatic cancer. In an interview with HT Lifestyle, Dr Sachiv Nanda, Chief Dental Surgeon (MDS) Prosthodontist, Ruby Hall Clinic Pune, identified Porphyromonas gingivalis as the bacteria that contributes to the development of cancer.

Symptoms of pancreatic cancer in the later stages include yellowing of the skin, pain in the upper abdomen, dark urine, itchy skin, nausea and fatigue. (Shutterstock)
Symptoms of pancreatic cancer in the later stages include yellowing of the skin, pain in the upper abdomen, dark urine, itchy skin, nausea and fatigue. (Shutterstock)

“Porphyromonas gingivalis, which is commonly associated with gum disease, has been found at high levels in the saliva of individuals with pancreatic cancer. Studies suggest that it may contribute to cancer development by creating an inflammatory environment and potentially residing within cancer cells. While Porphyromonas gingivalis has been the most studied, other oral bacteria may also play a role in pancreatic cancer risk,” said Dr. Sachiv Nanda.

Also read: Pankaj Udhas had pancreatic cancer; know all about the disease

inflammation:

Oral bacteria can cause inflammation, which is a known risk factor for various cancers.

Direct effect on pancreatic cells:

Some research suggests that these bacteria may directly damage pancreatic cells, which may increase the risk of cancer development.

Changes in the pancreatic environment:

The presence of oral bacteria in the pancreas may create favorable conditions for the growth of cancer cells.

Also read: Pancreatic cancer: Know everything from symptoms to treatment

Precautions and Future Directions:

Pancreatic cancer is a complex disease that is influenced by various genetic, environmental and lifestyle factors. Smoking, chronic pancreatitis, diabetes, obesity and a family history of pancreatic cancer may also contribute to the development of cancer.

Also Read: World Pancreatic Cancer Day: 5 early warning signs that should not be ignored

Exposure to chemicals and heavy metals:

Exposure to chemicals such as beta-naphthylamine, benzidine, pesticides, asbestos and benzene, and heavy metals may also increase the risk of pancreatic cancer.

physical activities:

People who engage in physical activity have a lower risk of pancreatic cancer than those who do not engage in any form of physical activity.

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