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ANI | | Posted by Akanksha AgnihotriTokyo
Aug 07, 2024 04:19 PM IST
Researchers at Osaka Metropolitan University found that antioxidants from Ecklonia cava seaweed may help prevent Parkinson’s disease by reducing neuronal damage.
The neurodegenerative condition known as Parkinson’s disease is triggered by the loss of neurons that produce dopamine, a neurotransmitter essential for both motor control and cognitive function. The number of people suffering from Parkinson’s disease is increasing rapidly as the world’s population ages. Overproduction of reactive oxygen species damages neurons, which causes Parkinson’s disease. Because the buildup of reactive oxygen species kills dopaminergic neurons, which control the dopamine neurotransmitter, it must be suppressed. Since only symptomatic treatment is now available, therapeutic regimens and preventive measures must be developed. (Also read: This coach has something important to tell you about Parkinson’s disease ,
Fortunately, Akiko Kojima-Yusa, Associate Professor at the Graduate School of Human Life and Ecology, Osaka Metropolitan University, led a research group that has verified the physiological effects of Ecklonia cava polyphenols, seaweed antioxidants, on the prevention of Parkinson’s disease.
In this study, two types of motor function tests were conducted using Parkinson’s disease model mice that were fed antioxidants daily for a week and then given rotenone. The results showed that motor function, which was reduced by rotenone, was restored. There was also improvement in intestinal motor function and colon mucosa structure, a special tissue that covers the colon.
In addition, cellular experiments using Parkinson’s disease model cells verified the biochemical interactions of the preventive effect of Ecklonia cava. The verification results showed that antioxidants activate the AMPK enzyme (adenosine monophosphate-activated protein kinase), an intracellular energy sensor, and inhibit the production of reactive oxygen species that cause neuronal cell death. (Also read: Dance, music therapy may be helpful in managing Parkinson’s disease: Study ,
“This study shows that Ecklonia cava antioxidants can reduce neuronal damage by inhibiting AMPK activation and the production of intracellular reactive oxygen species,” said Professor Kojima-Yusa. “It is expected that Ecklonia cava will be an effective ingredient in the prevention of Parkinson’s disease.”
This story has been published from a wire agency feed, no changes have been made to the text. Only the headline has been changed.
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