Brain metastasis from lung cancer: symptoms, treatment and prognosis

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Cancer is a major concern in the country. Metastasis is the condition when cancer spreads to a different distance from the primary location of cancer. For example, lung cancer has a tendency to spread to other parts of the body.

“One of the most serious complications of lung cancer is its potential to spread to other vital parts of the body, especially the brain,” said Dr Praveen Gupta. (Unsplash)

In an interview with HT Lifestyle, Dr Praveen Gupta, Principal Director and Head of Neurology at Fortis Hospital, said, “One of the most serious complications of lung cancer is that it can metastasize to other vital parts of the body, especially the brain. Brain metastasis is particularly common in lung cancer cases, with about 10% of new patients diagnosed with advanced non-small cell lung cancer (NSCLC) developing this complication. Lung cancer is the primary tumor source in 40 to 50% of all brain metastasis cases.”

Brain metastasis from lung cancer: symptoms

Persistent headachesThe condition is often more severe in the morning and may become worse over time.

RecoveryNew seizures are an important indicator of possible brain involvement.

cognitive impairmentMemory loss, confusion, and difficulty concentrating.

Behavioural changes: Mood fluctuations, irritability and behavioral changes.

Motor function difficultiesProblems with balance, co-ordination, or movement, as well as difficulty speaking.

Brain metastasis from lung cancer: treatment

Targeted therapyDesigned to specifically attack cancer cells while sparing normal tissues, based on the genetic makeup of the cancer

radiation therapy: This includes whole brain radiation therapy (WBRT) or stereotactic radiosurgery (SRS) to control tumor growth and reduce symptoms

Systemic chemotherapy: used to treat cancer throughout the body, including brain metastases, although its effectiveness may be limited due to the blood-brain barrier

palliative care: focuses on relieving symptoms and improving the quality of life of patients with advanced disease

Brain metastasis from lung cancer: prognosis

Dr. Praveen Gupta said, “Brain metastasis from lung cancer is a complex challenge that requires a multidisciplinary treatment approach involving oncologists, neurologists, and palliative care specialists. Prognosis largely depends on the success of treatment and the extent of brain involvement. Despite advances in therapy, brain metastasis typically shows late progression, resulting in reduced life expectancy compared to lung cancer patients without brain metastasis.”

Also Read: Lung Cancer Awareness Month 2022: Easy-to-ignore lung cancer symptoms

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