World Alzheimer’s Day 2025: Neurologist alert women face double risk of development of Alzheimer’s compared to men

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World Alzheimer’s Day 2025: The world is celebrated on 21 September as Alzheimer’s Day, which aims to spread awareness about Alzheimer’s disease; By arguing myths, warning of warning signs, highlight to which may be predetermined for better prevention. On this day, let’s take a look at who is the highest risk of developing Alzheimer’s. Dangerous, women have a higher risk than men.

Women are more likely to develop Alzheimer's due to biological, hormonal and genetic causes. (PC: Pexles)
Women are more likely to develop Alzheimer’s due to biological, hormonal and genetic causes. (PC: Pexles)

Also read: Can your teeth affect brain health? The expert revealed how dental issues can lead to serious conditions like Alzheimer’s

Dr. Bipan Kumar Sharma, Advisor Neurology, Kailash Deepak Hospital told HT Lifestyle that women are almost double the possibility of Alzheimer’s development.

He said, “Alzheimer’s disease affects women almost twice as men, and due to the fact that women live longer than men.” In addition, risk are more in women because a combination of biological, hormonal and genetic factors increases a woman’s sensitivity.

Here are some reasons that have shown from a neurologist that women can provide clarity on why there is more risk:

1. Menopause

Menopause is one of the contribution factors. (Shutterstock)
Menopause is one of the contribution factors. (Shutterstock)

Menopause is a major health milestone in a woman’s life, and Dr. Sharma revealed that hormonal changes play a role in determining sensitivity to neurodynative disorders. He said, “Estrogen, which has a protective effect on brain cells, falls significantly during midlife. This deficiency can change the use of brain structure and energy, as well as immune function, which can increase the risk of development of Alzheimer’s disease.”

He further stated that there may be a ‘important window’ during menopause when the hormone replacement therapy (HRT) can help, but it can not work to start too late and even harmful.

2. Genetics

Genetics play a major role in predetermination for neurodygenetic disorders. In this case, some genes are responsible.

In detail how this happens, Dr. Sharma said, for example, Apoe4 genes, a famous genetic risk factor for Alzheimer’s disease, have more impact on women than men. The fact is that women contain two X chromosomes, and some genes located on the X chromosome appear to avoid the normal silenting process, affecting brain aging and immune function. ,

3. Defence system

In addition, a woman’s immune system is usually more active than a male. The neurologist highlighted that it could be both an advantage and weakness.

He said, “A more reactive immune system can increase neuroinphlamation, which is one of the drivers of Alzheimer’s disease. This difference in immune behavior can contribute to the rapid buildup of amyloid plaques in women’s brains and rapid buildup of tau tangles.”

So for those who are already at risk of developing Alzheimer’s like women, it is important to become more attentive about your brain health by incorporating brain -friendly foods in your diet, to intensify cognitive skills to your brain, manage stress and visit a doctor for regular medical examination to monitor these risk factors.

Note the readers: This article is only for informative purposes and is not an option for professional medical advice. Always consult your doctor with any question about a medical condition.

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