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The genomic test for nutrition provides individual dietary insight by analyzing genetic variants that affects metabolism, nutrient requirements and prediction of the disease. In an interview with HT lifestyle, PD Hinduja Hospital and Senior Advisor to Gastro-Eye and Beriatric Surgeon, (Robotic and Laparoscopic) at MRC. Jaideep Palap, Khar shared his work on a genomic test for the diet plan. Also read Is the best diet written in your gene?
What are the major benefits?
He said, “Some gene variants affect how fat, carbohydrates, and protein are metabolized in your body. For example, one may have a gene version that causes poor carb processing.”
Dr. Sandeep Shah, Joint Managing Director, Newbug Diagnostic, explained, “We keep listening”.
Current limits
Asked how accurate current DNA tests are in providing actionable diet advice, and whether they can be trusted to guide dietary plans for conditions like obesity or metabolic syndrome, he said, “FTO, MC4R, PPARG, APOA2 and TCF7L2 have already been given 8-10 percent of the information like 8-10 percent,” Not clinically proven.
Dr. According to Shah, “Current DNA test genomes are based on the Wide Association Studies (GWAS), where scientists look at the genetic makeup of 1000 individuals with a disease/specialty and general individuals. Data are compared to reduce markers (single nucleotide polymorphism-SNP), which are more common in comparison to those who are more common. Plays an important role in regulating.
Dr. Palep said, “Food intolerance like lactose, gluten, etc. can be particularly connected to gene variants. Actionable genomics, eg, in vitamins and mineral metabolism, folate -forth genes, and vitamin D – GC genes are clearly connected. But the preventive care is not fixed for the dietary plan.”
Dr. Shah said, “What a genomic test role plays in identifying the conditions affected by diabetes or heart disease. Reduce the risk for metabolic diseases.”
Genomic tests vs traditional clinical methods
Does genomic tests for nutrition different from traditional clinical approach to providing diet insight? Dr. According to Shah, this approach varies from traditional clinical methods, which usually identifies current health issues rather than predicting future risks.
He said: “Traditional clinical approaches determine your current state of the body. For example, the deficiency of vitamin B12 is usually diagnosed after experiencing fatigue and numbness in hands and feet. A genetic test tells you whether you are predetermined for deficiency of vitamin B12, which are present in these persons.”
ethical consideration
Therefore, what moral thoughts should people keep in mind when choosing for genomic testing for dietary purposes? “Since there are no concrete random clinical tests supporting the principle of genomic testing for dietary purposes, these tests should be introduced to individuals with their informed consent, keeping them aware of scientific evidence or data deficiency for their use in day-to-day diet and nutrition scheme,” Dr. Palep said.
Dr. According to Shah, there are some parameters to check before selecting for genomic test: the scientific validity of the test, and whether genetic data is safely stored. “Genetics is an important component in our health. However, your lifestyle- sleep/exercise/stress also plays a role in the risk of disease. A genetic test acts like a health compass- to guide you intelligent options and a healthy, happy life,” he said.
Before selecting for genomic testing, consult with healthcare providers to understand the benefits and limitations.
Note the readers: This article is only for informative purposes and is not an option for professional medical advice. Always consult your doctor with any question about a medical condition.
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